8/14/2023 0 Comments Supplements for migraine with aura![]() ![]() Gallelli et al (2014) reported that "Magnesium increased the efficacy of ibuprofen and acetaminophen.".in pediatric migraine prophylaxis is poor". Orr (2014) suggested that "the quality of evidence." This doesn't say that much - nearly any kind of attention will affect migraine in a positive way. Kovacevic et al (2017) reported that "After 6 months of magnesium prophylaxis, disability due to migraine significantly decreased, whereas physical and psychosocial well-being improved.Von Luekner et al (2018) suggested in a systemic review that there is grade C (possible) evidence that 600 mg of magnesium dicitrate/day significantly decreases migraine severity.Khani et al (2021) suggested that "magnesium could enhance the antimigraine properties of sodium valproate in combination therapy and reduce the required valproate dose for migraine prophylaxis.Evidence for magnesium supplements as prophylaxis: ![]() There are about a dozen genes that result in hypmagnesiumia - but these are extremely rare in clinical medicine, and finding them does not contribute to therapy (Viering et al, 2017). Incomplete reabsorption causes magnesium wasting (Viering et al, 2017). Magnesium is regulated through the kidney, where it is reabsorbed. This means that it is especially important to take magnesium supplements for migraine prevention, if you take a PPI. Magnesium absorption is reduced by some stomach medications for reflux, called proton pump inhibitors. Magnesium in the blood reflects a balance between absorption in the gut and elimination through the kidney. Still, magnesium is probably very safe, and for this reason it is often recommended for children. The evidence for prophylaxis of migraine by magnesium in adults is reasonable, but the evidence for use in children as well as an abortive is weak. A little known aspect of migraine is that they are more likely when magnesium blood levels are low, and some migraines can be aborted by large amounts of magnesium, usually given in the emergency room (Sun-edelstein et al, 2009). Migraines are an immensely common human problem, affecting about 15% of the entire population (mainly women). Medications for reflux, proton pump inhibitors, can reduce migraine absorption.Magnesium supplements help prevent migraine. ![]()
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